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Arsenic trioxide combined with TACE prevents extrahepatic metastases and prolongs survival time or improves quality of life in patients with HCC [169,170,171,172,173], and arsenic trioxide injection has shown promising results in the treatment of HCC, with an analgesic effect [168]

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68,69 Conversely, CKD in its later stages also increases the risk of bleeding due to platelet dysfunction

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