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Valentine et al., 2008)

Energy Production: Glutathione is involved in various metabolic processes, including the production of adenosine triphosphate (ATP), which is the primary energy currency of cells

IS significantly increased the levels of reactive oxygen species (ROS) and malondialdehyde (MDA), while inhibiting antioxidant defense mechanisms such as superoxide dismutase (SOD) and glutathione (GSH), which is consistent with oxidative stress as a key driver of chronic kidney disease (CKD) progression ( To further investigate the signaling mechanisms underlying AST-mediated protection in CKD, we focused on the Nrf2/HO-1 pathway, a central regulator of cellular antioxidant defense

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These compounds exhibit significant pharmacological effects in the treatment of thyroid diseases and DM ( Scrophulariae Radix and their mechanisms of action are summarized in Table 1

10.1021/acs.est.6b01974 Environ