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Description

Our detailed report on the effects of DZN using in vivo and in vitro models provides essential data for studies on environmental male reproductive toxicity, subfertility, and infertility

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Cumulative tissue repair requires time, and early symptomatic improvements may underestimate the full potential of ongoing treatment

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In these cases, the liver may not be able to properly metabolize vitamin B12, leading to a build-up of the vitamin in the body

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The selective ULK1/2 inhibitor, DCC-3116, synergizes with the KRASG12C inhibitor sotorasib to suppress KRAS-driven LC, whereas this combination has been assessed only in early preclinical stages and lacks predictive biomarkers for patient stratification (17)

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