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Cisplatin is associated with severe adverse effects including nephrotoxicity, peripheral neuropathy, and ototoxicity

Versus GLP-1 agonists GLP-1 agonists like semaglutide and tirzepatide have become popular for metabolic optimization and weight loss

Factors affecting speed include starting weight, diet quality, activity level, sleep, stress, and genetics

GLP-1 stands for glucagon-like peptide-1, a naturally occurring hormone involved in: Appetite regulation Blood sugar control Insulin secretion Digestion Feelings of fullness A GLP-1 receptor agonist treatment mimics the effects of this hormone, helping individuals feel satisfied with smaller amounts of food while supporting healthier blood sugar regulation

8.6 1.8 mM vs Y211A

doi: 10.1016/j.cmet.2009.02.002 38 WangTJLarsonMGVasanRSChengSRheeEPMcCabeEet al