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Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025

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N-acetylcysteine administration prevents nonthyroidal illness syndrome in patients with acute myocardial infarction: a randomized clinical trial

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Prolotherapy vs

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doi: 10.1126/science.1232458 338 SuzukiA.SternS

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Household incomes varied widely, with the largest share earning $75,000 to $99,999 annually

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& Gil, A

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