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For example, it is the underlying cause of the well-known neurotoxicity induced by cisplatin (Cis-DDP), which often leads to the discontinuation of chemotherapy based on Cis-DDP

We then assessed whether LCS3 inhibits the downstream products of GSR and TXNRD1 activity within cells

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It enhances T cell activity by blocking CTLA-4, a protein that suppresses immune responses

The initiative, dubbed Operation TrialBlazer, aims to answer industry criticism that it can be difficult to obtain regulatory approval to test new drug candidates in the US

Kesiktas, Fatma Nur, et al