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[182] involving obese and pre-diabetic/ diabetic patients for its potential dietary and therapeutic benefits
The timelines here come from preclinical (mostly rodent) studies and clinical-practice observation, and they are ranges, not promises
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Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]
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