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doi: 10.1046/j.1365-313x.2000.00743.x

Although most drugs are metabolized by the liver, some nephrotoxicants are known to be dependent on kidney metabolism as this organ also expresses Phase I (CYPs) and Phase II (GSTs) enzymes (Anders 1980)

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Beyond fat loss, Tesamorelin increases lean body mass by 1.42 kg across randomized clinical trials, improves lipid profiles (reducing triglycerides by 48 mg/dL and total cholesterol by 8 mg/dL at 52 weeks), and lowers hepatic fat fraction by 4.9% at 12 months in patients with NAFLD