Im very bullish on this, even though the only thing that shows that it helps with depression was an animal study that shows that its 20 times more robust than antidepressants
The treatments were performed for 24 h
Notably, Tie-2 is not only a marker of endothelial cells, but is also expressed by proangiogenic monocytes and pericytes [80]
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In conclusion, combination of metformin and liraglutide has synergistic protective effects on endothelial function