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Therefore, MedTech companies should focus on the five essential steps mentioned before to prepare for success in a healthcare landscape directly shaped by GLP-1 advancements

Experimental compounds like retatrutide should be reserved for formal clinical trials

Important caveat on cross-trial comparisons: Retatrutides 28.3% should not be directly compared with Mounjaros 22.5% as if it is a 5.8% absolute improvement established by head-to-head evidence

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Optimal dosing, duration, and patient selection are still under investigation