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Often referred to as the 'satiety hormone', leptin signals to the brainspecifically the hypothalamuswhen the body has sufficient energy stores, thereby reducing appetite and increasing energy expenditure

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Weeks 1-4: 0.25 mg per week (starting dose) Weeks 5-8: 0.5 mg per week Weeks 9-12: 1.0 mg per week Weeks 13-16: 1.7 mg per week Week 17 onward: 2.4 mg per week (regular dose) The slow increase helps with side effects

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Kim DM, Hyun SS, Yun P, Lee CH, Byun SY (2012a) Identification of an emulsifier and conditions for preparing stable nanoemulsions containing the antioxidant astaxanthin