Novo Nordisk found evidence of compounded drugs with impurities or no semaglutide, according to a news release in May
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Doses of semaglutide ranging from 0.1-1.6 mg resulted in a 2.1%, 7.0%, 13.0%, 37.5%, 51.2%, and 63.6% respective dose-dependent increases in the proportion of patients that achieved a 5%, or greater, reduction in weight loss
The OFA additionally argued that even producers of FDA-approved semaglutide revealed in a recent SEC filing that the supply constraints and drug shortage notifications will continue into the foreseeable future. Given these disclosures, the OFA said the FDAs decision to end the shortage is arbitrary, capricious, and contrary to law, one that serves to benefit special interests, raise drug prices, and deprive much of the public access to a needed medicine. Compoundingthe process by which pharmacies and other parties produce their own formulations of FDA-approved drugscan help physicians address specific needs of their patients
Some clinicians argue that the weekly B12 bolus from the compound is perfectly adequate
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