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Effect of ochratoxin A on redox-regulated transcription factors, antioxidant enzymes and glutathione-S-transferase in cultured kidney tubulus cells

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370 ROS contribute to tumorigenesis through multiple processes, including causing oxidative DNA damage, genomic instability and inflammatory stress to drive malignant transformation, and acting as a messenger to regulate signaling pathways to support tumor initiation, development, and angiogenesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Harris I.S., Treloar A.E., Inoue S., Sasaki M., Gorrini C., Lee K.C., Yung K.Y., Brenner D., Knobbe-Thomsen C.B., Cox M.A., et al