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It works by attaching to GHRH receptors in the pituitary gland
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Supplementing zinc in deficient individuals may restore normal GH responsiveness to secretagogues
That means: Legal to purchase from licensed peptide vendors (for research use only) Not approved as a prescription medication Some compounding clinics may prescribe it off-label for anti-aging or performance Ipamorelin is not approved by the FDA but is available through compounding pharmacies
The idea is not baseless: dose-response curves for GH secretagogues do plateau, and the Bowers work explored GHRP across a 0.1 to 1.0 mcg/kg range, so a saturation region in that neighborhood is a reasonable-sounding extrapolation
10.1164/rccm.201307-1289LE Am J Respir Crit Care Med
