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Mitochondrial permeability transition pore in ASD Under physiological conditions, the IMM is impermeable to most molecules and ions

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J Neuroinflammation 16:142 Ji G, Liu M, Zhao XF, Liu XY, Guo QL, Guan ZF, Zhou HG, Guo JC (2015) NF-kappaB signaling is involved in the effects of intranasally engrafted human neural stem cells on neurofunctional improvements in neonatal rat hypoxic-ischemic encephalopathy

You start with 3 mg each day, then you may move up to a higher dose

But the effect size is modest and conditional