Other side effects Very common (may affect more than 1 in 10 people) feeling sick (nausea) this usually goes away over time diarrhoea this usually goes away over time low blood sugar (hypoglycaemia) when this medicine is used with medicines that contain a sulfonylurea or insulin
Head-to-head comparison While there haven't been direct studies comparing these two medications, meta-analyses examining multiple studies suggest semaglutide (Ozempic/Wegovy) produces significantly greater weight loss than phentermine
Protein targeting
In contrast, real-world evidence suggests incremental benefits across MACE, heart failure, and renal outcomes, supporting the hypothesis that complementary mechanisms of action may translate into broader protection in clinical practice
Ha S-H, Jin F, Kwak C-H, Abekura F, Park J-Y, Park NG, Chang Y-C, Lee Y-C, Chung T-W, Ha K-T, Son J-K, Chang HW, Kim C-H (2017) Jellyfish extract induces apoptotic cell death through the p38 pathway and cell cycle arrest in chronic myelogenous leukemia K562 cells
You strongly prefer brand-name medication