As with doxorubicin, cisplatin treatment also results in ROS generation, which is neutralised by the NADPH-powered glutathione system, warranting investigation of this strategy for other forms of chemotherapy which are detoxified via this system
As mentioned above, ferroptosis could be induced to exert anti-tumor functions via signaling pathway modulation, non-coding RNA expression, DNA methylation, histone modification, CSCs, microenvironment remodeling, and so on
R., Asbaghi, O., Naeini, F., Afsharfar, M., Mirzadeh, E., & Naserizadeh, S
Human mutation data reported
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Preparation of poly(acrylic acid) hydrogel by radiation crosslinking and its application for mucoadhesives