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This matters because your body naturally makes less collagen as you age and the collagen you have left breaks down faster, so supporting that process directly is more useful than masking the surface

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Skipping doses or discontinuing treatment prematurely may affect the desired outcomes

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De Tullio MC, Paciolla C, DallaVecchia F, Rascio N, DEmerico S, De Gara L, Liso R, Arrigoni O (1999) Changes in onion root development induced by the inhibition of peptidyl-prolyl hydroxylase and influence of the ascorbate system on cell division and elongation