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A 2024 study in Frontiers of Endocrinology showed a significant relationship between GLP-1 drugs and several mental health-related adverse events: Stress Eating disorders Fear of injections Sleep disorders Binge eating Fear of eating Self-induced vomiting Other concerns regarding mental health and GLP-1 drugs include questions about impacts on neurotransmitters and whether the same effects that decrease food noise may decrease enjoyment of different activities

Gottlob K, Majewski N, Kennedy S, Kandel E, Robey RB, Hay N

Conclusion The interactions between the endocrine and circadian system are complex