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In addition, the activated miR-29c-5p via induction of AKT signaling promotes the expression of growth-associated phosphoprotein 43 (GAP-43), improving neuronal growth and synaptic plasticity (Holahan 2017)

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In the semaglutide group, the participants body weight was reduced, on average, by 9.4% compared to a reduction of 0.9% among the adults in the placebo group