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as the typical rate of progression in PD is approximately 3 UPDRS points per year which was not evident in the exenatide exposed group (albeit a longer duration and larger patient number clinical trial is needed)

Taken together, these studies represent a significant shift in how the medical community views GLP-1 receptor agonists, moving beyond diabetes and obesity management into the realm of addiction medicine

The trough, conversely, is higher

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Our results agree with previous data showing that TIR significantly activated PI3K/AKT/GSK3 signaling pathway ameliorating insulin resistance in the hippocampus of diabetic rats [25]