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The intent-to-treat population included all patients who were treated with at least one dose of study medication and provided both a baseline assessment and at least one post-baseline efficacy result

Phase II trial data published in the New England Journal of Medicine (2023) demonstrated meaningful weight reduction in adults with obesity

No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in response between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out

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It is associated with a wide variety of conditions that include physiologic changes, inflammatory diseases, hormonal disorders, drugs and chemicals, benign and malignant neoplasm, and other non-melanotic conditions

Also, keep in mind that spermatogenesis, the process of sperm formation, takes about 2-3 months