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oral or injectable tirzepatide

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The metabolic benefits they produce have implications for cardiovascular disease, liver health, diabetes management, and more

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Side Effects and Adverse Events The side effects for both medications are generally gastrointestinal, particularly during the dose-escalation phase: Nausea Vomiting Constipation Diarrhea Rare but serious adverse events include: Pancreatitis Thyroid tumors (observed in animal studies) Hypoglycemia when combined with other glucose-lowering drugs Tolerability varies by individual, and while most side effects diminish over time, they remain a barrier to long-term adherence for some patients

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Ledezma-Tejeida D

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Where a claim rests on retracted work, that status is stated alongside it

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Another amylin and GLP-1 agonist pair being developed by Novo Nordisk is amycretin

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Rhodes ET, Goran MI, Lieu TA, Lustig RH, Prosser LA, Songer TJ, Weigensberg MJ, Weinstock RS, Gonzalez T, Rawluk K, Zoghbi RM, Ludwig DS, Laffel LM: Health-related quality of life in adolescents with or at risk of type 2 diabetes

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