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Summarizing, it can be highlighted that systemic iron overload is not common in autism, hence region-specific accumulation may promote oxidative stress and ferroptosis, damaging neurons and causing inflammation

We have individuals as young as 12 that can be on these therapies, and I have patients in their 90s on these therapies

doi: 10.1186/s12964-025-02328-3 171 KarpishehVFakkari AfjadiJNabi AfjadiMHaeriMSAbdpoor SoughTSHeydarzadeh AslSet al

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After 2 min of incubation at room temperature, ferrozine and saturate ammonium acetate (NH4Ac) were sequentially added to each tube and the absorbance was measured at 570 nm (BioTek EL x 800, Shanghai, China) within 30 min

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