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The presence of cholesterol in the niosomes formulation was considered important for keeping the assemblage integrity and physical stability and rigidity of these vesicles 60,61,62

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For example, an older adult with diabetes who is taking several medications and losing weight on semaglutide may face a higher risk of orthostatic hypotension than someone who does not have these factors

It has been reported that ALC affects mitochondrial respiration by increasing cytochrome oxidase activity and reducing glutamate dehydrogenase activity in rat mito- chondria, indicating a possible effect on neurotransmitter metabolism at a synaptic level [21,22]

Relative fold-changes for transcripts were calculated using the comparative 2 -CT method 42 (Livak and Schmittgen, 2001) and normalized to an actin control