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The key molecules in signaling pathways associated with glycolysis (e.g., PDK4), OXPHOS (e.g., IDH1 and KG), glutaminolysis (e.g., glutaminase), PPP (e.g., G6PD and NADPH), and P53 pathway are critically involved in regulating ferroptosis in ovarian cancer [12]

Accounts of Chemical Research 46 , 662671, (2013)

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3) Clinical relevance: LN patients with Grade III/IV disease show higher ferroptosis levels, which correlate strongly with renal function decline (221)

Chen, T., & Zhao, X

Although there have been some advances in the treatment of sepsis, mainly focused on broad-spectrum antibiotics, mortality rates remain high, urging for the search of new therapies