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Similarly, in an earlier study, the up-regulation of iNOS in the intestinal epithelial cells (IECs) has been closely associated with the initiation and maintenance of intestinal inflammation in IBD, which can be potentially used as a non-invasive blood-based biomarker of IBD, as documented (139)

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When semaglutide is stored improperly in warm environments like hot cars, bathrooms, or sunny windowsills, the medication's concentration decreases, meaning each injection delivers less active compound than intended