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The authors thank Irene Orera from the Proteomics Facility of the Centro de Investigacin Biomdica de Aragn for the MRM-MS analysis

In addition, prolonged exposure to pharmacologic doses of long-acting GLP-1 RAs induces tachyphylaxis for the effects on gastric emptying, and that is why nausea vanishes quickly after the beginning of treatment in most patients [19]

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