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Consider this scenario: a patient following a mostly vegetarian diet starts compounded semaglutide and notices significant fatigue in weeks two through four

B12 deficiency can also be an issue if you have had weight loss surgery, have a very poor diet, or follow extreme or restrictive diets for a long time

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Older adults can also benefit, as B12 absorption tends to decrease with age

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How Long Does It Take for a B12 Injection to Work How Long Does It Take for a B12 Injection to Work If you are wondering how long does it take for a B12 injection to work, most people notice changes within days to two weeks