Eligible patients were aged 21 years or older, had type 2 diabetes, were at moderate risk for cardiovascular disease and did not have a history of thyroid cancer
veterans with type 2 diabetes, the WashU Medicine team found GLP-1s are tied to a reduced risk of developing substance use disorders across all major addictive substances and to a reduced risk of severe harm, including overdose and death, in people who already have such disorders
GLP-1 did not increase myocardial oxygen consumption or blood flow in humans or in swine, increasing p38-MAPK activity in lean, but not obese cardiac tissue [48]
The dosing is gradually titrated upward over several weeks to minimize gastrointestinal side effects
Restaurant meals that you would have finished easily now provide two or three servings
The sublingual version typically comes in concentrations ranging from 1 mg/mL to 5 mg/mL, with daily doses usually starting at 0.5-1 mg and escalating over several weeks