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Synthesis and biochemical applications of a solid cyclic nitrone spin trap: a relatively superior trap for detecting superoxide anions and glutathiyl radicals

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2.6.1 Nrf2 signaling Nrf2 is a crucial transcription factor that plays a significant role in preserving mucosal balance by inhibiting the excessive production of ROS in IBD.Nrf2 has a dampening effect on the inflammatory response and the damage to the mucosal lining through its antioxidant actions (87)

Please refer to the Regulatory Impact Analysis (section VI

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