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Furthermore, some animal studies also did not report any change in glutathione content in different tissues (such as the liver, lens and erythrocytes) in riboflavin-deficient animals ( Reference Bates 27 Reference Rao and Bhat 29 )

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VEGFR2 activation Akt phosphorylation induction of endothelial nitric oxide synthase (eNOS) NO release local vasodilation and formation of new blood vessels at the injury site