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High doses of ascorbyl palmitate (equivalent to 600 mg/kg of free vitamin C) given concurrently with acetaminophen prevented the elevation of serum liver enzymes in mice and reduced acetaminophen-mediated mortality (Jonker 1988)

Mean baseline serum B12 levels were reported in this study but it is not clear what proportion of patients had B12 deficiency

Congestive heart failure Congestive heart failure (deterioration of the hearts ability to pump blood) is associated with a high risk of sudden cardiac death from arrhythmia (Nessler 2007

Given that melasma exhibits heterogeneous features, such as variations in pigment distribution and lesion depth, this lack of histological differentiation may affect the interpretation of treatment responses

hydrophila , where all treated fish showed significant protection