This colorimetric assay is based on the GST-catalyzed reaction between reduced glutathione and GST substrate, 1-chloro-2, 4-dinitrobenzene (CDNB)
In a cellular model of CF, ASOs were designed to target the inhibitory secondary mRNA structures in the uORF of the 5 UTR on the CFTR mRNA transcripteffectively increasing both the expression and function of CFTR [88]
Shuster L, Faubion S, Sood R, Casey P
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Each vial is vacuum-sealed to maintain stability and bioactivity