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Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities

Biochemical analysis Serum urea and creatinine levels While the serum urea level of the MTX group significantly decreased, the serum creatinine level significantly increased compared with the control group (Table 2)

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Symptoms are typically worst with the elbow bent for long periods (sleeping with arms folded, talking on the phone, leaning on an armrest)

In addition, glutathione may be consumed in conjugation reactions