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The results showed that among phosphoproteins, 24 were upregulated (FC 1.2) and 52 were downregulated (FC 0.83) in fibroblasts from keloid versus those from adjacent skin (Supplementary Data 1)

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Expression of the target genes was normalized to the geometric mean of 3 reference genes in BF (hydroxymethylbilan synthase, ribosomal protein L37a, and ribosomal protein S15) and 3 reference genes in the liver (beta-2-microglobulin, hydroxymethylbilan synthase, and ribosomal protein S15)

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Reactive oxygen species detection Cells were processed as per manufacturers (Invitrogen, C10444) instructions