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Although beneficial under normal circumstances, the drug efflux attributes of P-gp can be the leading cause for diminishing, if not nullifying, the efficacy of anti-cancer agents against cancer cells [11, 13, 28, 32, 34]

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It belongs to a novel class of drugs known as triple agonists, meaning it simultaneously activates three hormone receptors: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor