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These results indicated that tumors with high ACTL6A expression, which rely more heavily on GSH metabolism than those with low ACTL6A expression, are more sensitive to ferroptosis inducers or GCLC inhibitors

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Protein analysis revealed that melatonin increased levels of oxidative phosphorylation complexes V, III, and II, and elevated key antioxidant proteins NRF2 and KEAP1 in aging HGL5 cells (Fig

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It is one of the main reasons we lose brain cells as we age

10.1016/j.mrfmmm.2011.10.008 Mutat