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doi:10.1016/j.xcrm.2025.102214 Moiz A, Filion KB, Tsoukas MA, Yu OHY, Peters TM, Eisenberg MJ

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Some are made following rigid pharmaceutical guidelines, while others are made by compounding pharmacies or online sellers with minimal regulation

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Despite the definite clinical need for evidence-based treatments to correct problems with sleep and circadian rhythms, no well-designed studies on the efficacy of melatonin administration in sleep and circadian rhythms in bipolar disorder were identified [55]

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