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Activated microglia release IL-1, which stimulates astrocytes to secrete VEGF and proinflammatory chemokines like CXCL2, CCL2, and CCL20, further exacerbating BBB dysfunction [240]

Lyophilization removes solvent under controlled temperature and vacuum conditions, producing a stable dry peptide material suitable for laboratory storage and transport

Mechanisms and biological relevance of lipid peroxidation initiation

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Muscle weakness: Particularly in those with pre-existing conditions affecting muscle function