glp 1 for mash Why are GLP-1 agonists being used to treat patients with nonalcoholic fatty liver disease? mash glp 1 Incretin-based therapies

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Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

The researchers discovered that small-molecule GLP-1 drugs significantly reduced how much dopamine, a neurotransmitter thats commonly associated with reward-motivated behaviors, was released, essentially changing the animals perception of how rewarding that food is. Gler hopes that his teams discovery can help guide future efforts in designing GLP-1 drugs that target specific parts of the brain, such as the reward center

Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food. Diabetes, vol

The comprehensive implications across several systems are outlined in Table 1

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