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Someone who is taking or thinking about taking tirzepatide should consider switching to a contraceptive other than the pill, she says, adding that there are many options for birth control, so the fact that tirzepatide may make oral methods less effective shouldnt deter people from taking the medication

The decreased expression and signaling of TLRs, essential for recognizing pathogen-associated molecular patterns (PAMPs), further impair the ability of aging macrophages to phagocyte apoptotic cells and respond to pathogens

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For semaglutide, the deadlines were set for April 22, 2025 (503A) and May 22, 2025 (503B)

It was later found to be effective in aiding weight loss as well

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