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For semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda), the Summaries of Product Characteristics confirm that the injection site does not significantly affect the pharmacokinetics of these medications
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However, their potential role in mitigating RV mitochondrial dysfunction in PH has not been thoroughly investigated
Each subject received in a random order a single subcutaneous dose of 1.2 mg liraglutide and placebo at an interval of 48 h, with subsequent clinical follow-up in the metabolic ward, during which blood pressure was monitored for the following 24-h and 24 h urinary samples were collected to assess sodium excretion
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