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2245-A PROJECTION OF THE CLINICAL BURDEN OF NAFLD IN US ADULTS FROM 2020-2050: A MODELING STUDY Phuc Le 1 , Moosa Tatar 1 , Srinivasan Dasarathy 2 , Naim Alkhouri 3 , William Herman 4 , Abhishek Deshpande 1 , Glen Taksler 1 , Wen Ye 5 and Michael Rothberg 1 , (1)Cleveland Clinic, (2)Cleveland Clinic Foundation, (3)Arizona Liver Health, Phoenix, AZ, (4)University of Michigan Medical School, (5)University of Michigan Background: Following the alarming rise in prevalence of obesity and diabetes, nonalcoholic fatty liver disease (NAFLD) is projected to become the leading indication for liver transplant (LT) in the United States in the next decade
(New York, NY: Wiley Intersci.), 153196
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At t=0, 8, 16, 28 and 38w mice were euthanized, and liver, WAT depots and gut were analyzed biochemically, histologically and by lipidomics and transcriptomics together with circulating factors to investigate the sequence of pathogenic events and organ cross-talk during NAFLD development
Urata Y., Yamamoto H., Goto S., Tsushima H., Akazawa S., Yamashita S., Nagataki S., and Kondo T
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