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In this article, Ill give a quick background on Medicares long-standing exclusion of weight-loss medications, explain the BALANCE and Bridge models, and break down what this means for patients, physicians, and the health system

For tirzepatide, only the Zepbound KwikPen is available under the Bridge

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Patients using commercially available weight loss patches have mixed opinions about the efficacy of the patches

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Interestingly, inhibiting WNT1-expressing spinal afferents increases food intake [37], suggesting a physiological role for this sensory cell type in suppressing food intake