These pathways include the cyclic AMP-protein kinase A (cAMP-PKA) pathway, phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling, and nuclear factor kappa B (NF-B)-mediated cascades, which regulate cell proliferation, apoptosis, and migration
Statements Author contributions GC: Conceptualization, Data curation, Investigation, Methodology, Writing original draft, Writing review & editing
it has only been described in SUM
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Many patients benefit from staying on a lower maintenance dose indefinitely rather than stopping entirely
PCBs via the action of CYPs are converted into the active metabolites [94]