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Leslie N.R., Downes C.P., PTEN: The down side of PI 3-kinase signaling.Cell

Astrocytes release glutamate via cystine/glutamate antiporter upregulated in response to increased oxidative stress related to sporadic amyotrophic lateral sclerosis

Dietary changes, such as avoiding mold-containing foods like cheese, fermented products, and certain nuts, can also reduce exposure

In some regions, 8-20% of people have a more severe form, reducing enzyme activity to just 30%

Additional research is required to establish their efficacy, safety, and to develop more effective treatment strategies

Withdrawal syndromes also resolve on their own over exactly the timescale studied