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This includes: Semaglutide (Ozempic, Wegovy, Rybelsus) Tirzepatide (Mounjaro) Dulaglutide (Trulicity) Liraglutide (Saxenda) Most prescribing information suggests discontinuing these medications at least 2 months before attempting conception due to potential fetal harm observed in animal studies, including: Growth restriction Delayed skeletal development Increased pregnancy loss There is limited human data, but the risk signals are sufficient to justify a cautious, prevention-first approach

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The intrinsic, or mitochondrial, pathway is activated by honeys polyphenolic components that cause mitochondrial membrane depolarization and activate caspases 3, 7, and 9 (84, 85)