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At the cellular level, intracellular uptake in the nasal epithelium may involve multiple endocytic pathways, including clathrin-mediated endocytosis, caveolae/lipid raft-associated internalisation, macropinocytosis, and receptor- or adsorptive-mediated transcytosis, which can collectively influence the efficiency of CNS targeting (Dhuria et al., 2010, Pardeshi and Belgamwar, 2013)

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doi:10.1055/s-0040-1718965

A., Taylor, R