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Cell Microbiol (2015) 17:13145.10.1111/cmi.12343 49 ImaiYKubaKNeelyGGYaghubian-MalhamiRPerkmannTVan LooGet alIdentification of oxidative stress and toll-like receptor 4 signaling as a key pathway of acute lung injury

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To view a copy of this licence, visit About this article Cite this article Campforts, B., Drukker, M., van Amelsvoort, T

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Tsai and colleagues note that even though meds like Wegovy and Zepbound are effective in helping people shed pounds, the drugs' "high cost and high rates of gastrointestinal adverse effects can lead to treatment cessation and subsequent weight regain." Demand for weight-loss meds has also outstripped supply, so it's possible that the number of weight-loss surgery patients may rise again if "ongoing national shortages" of GLP-1s continue, the research team added